Composition :
Each 1 gm contains:
- Doxycycline (as hyclate) 400 mg + Bromhexine (as hydrochloride) 40 mg
Properties :
Doxycycline: has broad spectrum activity inhibiting both aerobic and anaerobic gram-posi�tive and gram-negative bacteria, mycoplasmas, chlamydiae, rickettsias and some protozoa.
Bromhexine is a mucoregulator. By activating the secretion of the seromucous glands, It
breaks down the network of acid glycoprotein fibres found in mucoid sputum, which are
mainly responsible for the characteristic viscosity.
Mechanism of Action:
Doxycycline inhibits bacterial protein synthesis. Doxycycline binds to the 30S ribosomal
subunit, which prevents the tRNA from binding to the ribosome. This prevents the mRNA
from being translated into protein, which is essential for bacterial growth and reproduction.
Bromhexine acts by inhibiting neuraminidase, stabilizing lysosomes, increasing ciliary
activity, hydrating mucus, and exhibiting anti-inflammatory effects.
Strength points of Hexacycline:
Hexacycline Synergistic effect: Doxycycline is a broad-spectrum antibiotic that is effective
against a wide range of bacteria, including Mycoplasma gallisepticum, which is a common
cause of respiratory infections in poultry. Bromhexine is an expectorant that helps to loosen
mucus and clear congestion. When used together, doxycycline and bromhexine can be more
effective than either drug alone in treating respiratory
infections.
Hexacycline Improved absorption: Bromhexine can help to improve the absorption of doxy�cycline, which means that it is effective in the lower doses.
Hexacycline is effective against a wide range of Gram-positive and Gram-negative bacteria,
making it a versatile antibiotic for poultry.
Hexacycline has a long half-life, meaning it remains in the body for an extended period,
providing prolonged protection against bacterial infections.
Hexacycline Reduced Respiratory Distress: By assisting in clearing mucus and improving
airway function, bromhexine may contribute to reducing respiratory distress in affected
poultry
Dose of whole product:
Broilers chickens: 0.5 gm of the product / 1 liter drinking water
Produced by EVA PHARMA distributor by Aleffat trading
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