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Antibiotics (11)

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Super Mox 40

Composition :
Each 100gm contains : Amoxicillin trihydrate                       48.6 gm Equiv. to Amoxicillin base                 40 gm Properties :
Supermox 40 :- - Is the trade name of amoxicillin trihydrate, a broad spectrum antibiotic. - Its bactericidal effect by collapse of the cytoplasmic membrane of the bacterial cell. - Its active against G+Ve bacteria ( Clostrisia , Staph , Strpt , Coryne ) & G-Ve bacteria ( E. Coli , Salmonella , Pasteurella haemophilus ) Indication :
Supermox 40 in indicated in the treatment of : - Poultry : Clostridial infections ( necrotic enteritis ) – Colisepticaemia fowel cholera – Salmonellosis – coryza - Calves – Lambs & Kids : Scour due to E.coli- salmonella. Staph & streptococcal infections. Pneumonia & urogental infections due to sensitive organisms Dosage & administration :
Supermox 40 is given orally via drinking water for Poultry : 20 mg amoxicillin base / kg b.wt. equive . to 100 gm of the product / 2000 kg b.wt. In drinking water ( one gm / 2 lit.) daily for 3-5 days ( 5 days in salmonella infections) for calves – lampbs & kids : 10 mg amoxicillin base / kg b.wt. equiv. to 0.5 gm / 20 kg b.wt. In drinking water twice daily for 3-5 days (5 days in salmonella infections) Warnings & Precautions : -Not used for prophylaxis in case of infection spread -Not used for layers - Used only for calves - Lambs & kids - Contraindicated in previous histort of allergy caused by B-lactam Withdrawal time : Calves – Lambs & kids : 14 days Poultry : 7 days Storage : store in a dry place away from direct sunlight Package : 500gm Manufactured by Arabcomed for Drugest pharmaceutical company distribution by "Aleffat trading "

Hexacycline

Composition : Each 1 gm contains: - Doxycycline (as hyclate) 400 mg + Bromhexine (as hydrochloride) 40 mg Properties : Doxycycline: has broad spectrum activity inhibiting both aerobic and anaerobic gram-posiïż½tive and gram-negative bacteria, mycoplasmas, chlamydiae, rickettsias and some protozoa. Bromhexine is a mucoregulator. By activating the secretion of the seromucous glands, It breaks down the network of acid glycoprotein fibres found in mucoid sputum, which are mainly responsible for the characteristic viscosity. Mechanism of Action: Doxycycline inhibits bacterial protein synthesis. Doxycycline binds to the 30S ribosomal subunit, which prevents the tRNA from binding to the ribosome. This prevents the mRNA from being translated into protein, which is essential for bacterial growth and reproduction. Bromhexine acts by inhibiting neuraminidase, stabilizing lysosomes, increasing ciliary activity, hydrating mucus, and exhibiting anti-inflammatory effects. Strength points of Hexacycline: Hexacycline Synergistic effect: Doxycycline is a broad-spectrum antibiotic that is effective against a wide range of bacteria, including Mycoplasma gallisepticum, which is a common cause of respiratory infections in poultry. Bromhexine is an expectorant that helps to loosen mucus and clear congestion. When used together, doxycycline and bromhexine can be more effective than either drug alone in treating respiratory infections. Hexacycline Improved absorption: Bromhexine can help to improve the absorption of doxyïż½cycline, which means that it is effective in the lower doses. Hexacycline is effective against a wide range of Gram-positive and Gram-negative bacteria, making it a versatile antibiotic for poultry. Hexacycline has a long half-life, meaning it remains in the body for an extended period, providing prolonged protection against bacterial infections. Hexacycline Reduced Respiratory Distress: By assisting in clearing mucus and improving airway function, bromhexine may contribute to reducing respiratory distress in affected poultry Dose of whole product: Broilers chickens: 0.5 gm of the product / 1 liter drinking water Produced by EVA PHARMA distributor by Aleffat trading

APSA MINT

Composition:-
Per 1 l
Eucalyptus oil              110 gm
Dl mentol                      51 gm
Betaine Hcl                    10gm
Vitamin C                       10gm
Indications: 
Nutritional supplement based on essential oils (eucalyptus and mint) indicated to increase ventilation capacity in the respiratory tract in pathological situations, post-vaccine reactions and stress in general.
Target species and dose:
 All species an/or animal categories: 250 mL/1,000 L of drinking water for 2 to 3 days. Swine: Pigglets and fattening pigs (<30 kg bw): 250 mL/1,000 L of drinking water for 2 to 3 days. Finishing pigs: 150 mL/1,000 L of drinking water for 2 to 3 days.
Form and packaging: 
Liquid. 500 mL
Manufactured by andres pintuluba spain distribution by "Aleffat trading "

Tylosol

Composition: - Tylosin  tartarate                                    110gm Equivalent to Tylosin                            100 gm Properties : Tylosin is a macrolide antibiotic which acts by inhibiting bacterial protein synthesis through binding to 50S ribosomal  subunits within cell wall . It has antibacterial spectrum that is essentially against gram +ve bacteria including (Actinomyces spp . Erysipelothrix rhusiopathiae), certain gram – ve. bacteria including Pasteurella spp and Fusobacterium necrophorum)and certain Spirochetes (as Treponema hyodysenteriae). Indications: Pre ruminant Calves: Treatment of pneumonia caused by Mycoplasma spp when the disease has been established in the herd. Broiler Chickens: Treatment of chronic respiratory diseases (CRD) caused by Mycoplasma gallisepticum and Mycoplasma synoviae when the disease has been established in the flock. Treatment and prevention of necrotic enteritis caused by Clostridium perfringens when the disease has been established in the flock Turkeys:  Treatment of infectious sinusitis caused by Mycoplasma gallisepticum. when the disease has been established in the flock Target species: Broiler Chickens, pre ruminate Calves, Turkeys Dosage and administration: by addition to drinking water From active ingredient Pre ruminant Calves: 10 – 20 mg tylosin per kg BW twice daily for 7 - 14 days. Turkeys: 75 – 100 mg tylosin per kg BW per day for 3 – 5 days Broiler Chickens: For the treatment of chronic respiratory disease: 75 – 100 mg tylosin per kg BW per day for 3 – 5 days. From whole product Pre ruminant Calves: 0.54 gm-1.08gm  of product per 50 kg BW twice daily for 7 - 14 days. Turkeys: 0.81 gm –1.082 gm /10 kg BW( 1 liter )  per day for 3 – 5 days Broiler Chickens: 0.81 gm –1.082 gm /10 kg BW( 1 liter )  day for 3 – 5 days Contra indications: It shouldn’t be used in layers producing eggs for human consumption Drug interactions Because tylosin is related to macrolides group, it interacts with Clindamycin (increase antagonism of effect) Side effects:Diarrhoea, epigastric pain Withdrawal period: Pre ruminant Calves (meat and offal): 12 days Turkeys (meat and offal): 2 days, Turkey (eggs): Zero days Broiler Chickens (meat and offal): 1 day, Chicken (eggs): Zero days Manufactured by Eva pharm distribution by "Aleffat trading "

Doxytest 40

Composition :-
 Each 100 gm contains : Doxycycline Hcl                                     52 gm Equive to Doxycycline base                 40 gm Indications : * Poultry & Turkey: - CRD due to mycoplasm & E.Coil infection. - Infectious coryza – air saculitis. - Fowl cholera – Colibacillosis – Salmonellosis infections. - Chlamydia and Rickettsia infections. * Calves & Lambs : Respiratory , Urogenital & digestive infections due to doxycycline sensitive micro – organisms Dosage and administration : - Poultry : 1 gm / 4 liter of  drinking water daily for 3-5 days. -Calves – Lambs : 0.25 gm / 20 kg b.wt.in drinking water daily For 3-5 days. Precautions and Warning : Not used for layers.  - - Not used for Lactating animals. Withdrawal period :- - Poultry : 10 days. - Calves & Lambs : 21 days. Storage : In cool and dry place at room temperature. Package : 500gm Manufactured by Arabcomed for Drugest pharmaceutical company distribution by "Aleffat trading "

Eimeria-Nil

Composition :- Each 100 gm contains: Amprolium hydrochloride                   26.3 gm Equiv. to Amprolium base                   25 gm Ethopabate                                              1.6 gm Properties & indication :- Eimeria-Nil is the trade name of amprolium which is a water soluble powder. Amproluim product its anticoccidial effect by preventing the uptake of thiamine ( vit.B1) by the coccidial cell . It acts on the early first generation of merozoites & schizonts (a sexual stage ). Ethopabate interferes with the folic acid synthesis . It has a great synergistic effect against all coccidial cells Eimeria-Nil is used in the treatment of coccidiosis in Chickens, Turkeys, which is caused by Eimeria tenella, Eimeria acervulina,Eimeria maxima , Eimeria necatrix, Eimeria brunette, wether the coccidian is caecal or intestinal. Dosage and Administration :- For Active Ingredient :- Poultry & Turkeys : 12-25 mg of Amprolium base / k.g.wt dissolved in drinking water once daily for 5-7 days. For Whole product :- Poultry & Turkeys : 0.75-1.5 gm / 1 litre of drinking water dissolved once daily for 5-7 days. Warning & Precautions : -Not to be used with layers -Not to be used with folic acid and thiamine Withdrawal Time : 5 days before slaughter. Side effect : -It may produce thiamine like deficiency. Storge : store in a dry place for away from sun light. Package : 500 gm Manufactured by Arabcomed for Drugest pharmaceutical company distribution by "Aleffat trading "

Chicktetra 70%

Composition: - Each 1 gm contains Oxytetracycline hydrochloride       757 mg Equi. To oxytetracycline base         700 mg Properties :

Oxytetracycline is a broad-spectrum antibiotic. It is mainly active against Gram-positive and Gram negative bacteria, aerobic and anaerobic, mycoplasma, Chlamydia and Rickettsiae It acts by reversibly to the ribosomal subunit 30S receptors to a blockage of the union between aminoacyl-tRNA to the site corresponding to the mRNA-ribosome complex messenger. Then inhibition of the protein synthesis and inhibits bacterial growth. Indications: Chicktetra is used for the treatment of: Broiler chickens: *Arthritis caused by Staphylococcus aureus. *Chronic Respiratory Disease (CRD) caused by Mycoplasma gallisepticum. *Infectious enteritis caused by E. coli. *Fowl cholera caused by Pasteurella multocida. *Fowl coryza caused by Haemophilus paragallinarum. *Gangrenous dermatitis caused by Clostridium spp. *Typhoid & paratyphoid caused by Salmonella  spp. Pre – ruminating calves: *Bovine pneumonia caused by Mycoplasma bovis , Pasteurella haemolytica , P. multocida & Haemophilus somnus. *Scours , neonatal diarrhea  caused by E. coli & Salmonella  spp. Target Species Broiler Chickens ,pre-ruminating calves Dosage and administration:

  by addition to drinking water From active ingredient  : Broiler chickens: 20mg of oxytetracycline /kg body weight 3-5 days Pre – ruminating calves: 10-30 mg / kg bodyweight 1-2 times daily From whole product Broiler chickens: 0.5 gm of product / liter of drinking water 3-5 days Pre – ruminating calves: 2.5gm7.5gm  of product /100 kg body weight 1-2 times daily Warning and precautions : Should be dissolved in water, before use. Prolonged or repeated use should be avoided Do not use in laying birds producing eggs intended for human consumption Contra indications hypersensitivity to oxytetracycline or any other substance from tetracyclines group. Side effects:  gastro-intestinal disorder and less frequently, allergic and photosensitivity reactions. Interaction with other drugs: should not be administered with antacids, gels containing aluminium, preparations containing vitamins or minerals as insoluble complexes will be formed, which decreases the absorption of the antibiotic. Withdrawal period Meat and offal:7 days Eggs: do not use in laying birds producing eggs intended for human consumption Storage: Keep on cool &dry place not exceeding 30° C. Keep out of reach of children. Manufactured by Eva pharm distribution by "Aleffat trading "

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